Study 2 - NMN for Sleep and Stress

The study provides evidences that NMN and NMNP treatment might alleviate PCPA-induced sleep disorders through regulating the oxidative stress.

Nicotinamide mononucleotide and NMN-rich product supplementation alleviate p-chlorophenylalanine-induced sleep disorders 

Objective

The objectives of this study was to investigate thesedtive and hypnotic effects of NMN and its derivative NMNP on insomnia mice model in order to explore the underlying mechanism of their effects on sleep regulation.

Subject

72 variable subjetcs 

Main results 

The main results of this study is that NMN and NMNP treatment reduced sleep latency, increased sleep duration, and improved sleep quality in PCPA-induced insomnia mice. It is suggested that NMN and NMNP may be potential therapeutic
agents for the treatment of insomnia and other sleep disorders.